Although many people take Percocet safely, it’s possible to become physically dependent on the drug, and abuse and overdoses do occur. So it’s important to follow your healthcare provider’s usage instructions carefully.
What Is Percocet?
Percocet is the brand name for a painkiller containing both oxycodone and acetaminophen.
It’s a controlled substance, available by prescription only, and can be formulated in a variety of strengths. Most forms of Percocet contain between 2.5 and 10 milligrams (mg) of oxycodone hydrochloride, and 325 to 650 mg of acetaminophen.
Side Effects
The potential side effects of Percocet include:
Oxycodone is a morphine-like substance that acts on the nervous system to change the brain’s perception of pain. Acetaminophen (Tylenol) is thought to inhibit certain pain-related chemicals in the body, thought its exact mechanisms of pain control are not fully understood.
DrowsinessConfusion or muddy thinkingConstipationNauseaDizzinessFlushing or sweating
In some people, Percocet may cause serious side effects, including difficulty breathing, severe lethargy and “pinpoint pupils.” These may be signs of an overdose and require immediate medical attention.
Safety Advice
To avoid serious side effects, Percocet use should be closely monitored in those with any of the following conditions:
Respiratory problems (including asthma or COPD)Circulatory problemsLiver or kidney diseaseSeizure disorders
Its use should also be carefully monitored in special populations, such as seniors, pregnant or nursing mothers and children. In most cases, Percocet use in these populations is avoided unless the benefits of the medication strongly outweigh the potential risks.
Physical Dependence
It’s possible to become physically dependent on Percocet, depending on how high the dose is and how long you’ve been taking it, as well on as your health status.
People who become physically dependent on Percocet may experience withdrawal symptoms if they abruptly lower their dose or stop taking the drug. If you’ve been prescribed Percocet, follow your healthcare provider’s instructions carefully.
The symptoms of Percocet withdrawal include:
YawningAnxietyIncreased heart rate and blood pressureRestlessnessNervousnessMuscle achesTremorIrritabilityChills alternating with hot flashesSalivationAnorexiaSevere sneezingLacrimationRhinorrheaDilated pupilsDiaphoresisPiloerectionNauseaVomitingAbdominal crampsDiarrheaInsomniaPronounced weakness and depression
Abuse and Overdose
Percocet is an opioid painkiller, one of the most commonly abused classes of prescription drugs. Abuse should not be confused with dependence. With Percocet abuse, drug use is compulsive and often non-medical.
Percocet overdose can occur if it’s taken more often than prescribed, or if the tablets are crushed or chewed, which can release too much medication at once. The potential for Percocet overdose also increases if it’s combined with other sedatives such as sleep aids or alcohol.
