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Why pemphigus occurs remains something of a mystery, but scientists have been able to establish that the immune system will suddenly target and attack proteins, called desmoglein, that help cells stick together. Pemphigus can occur on its own or manifest as a feature of certain autoimmune diseases or cancers. Pemphigus may also be triggered by certain drugs. The diagnosis typically involves a biopsy of the skin or mucous membrane. Treatment may include oral or injected steroids, immunosuppressant medications, intravenous antibodies, and biologic drugs....

League leaders Steaua went ahead after referee Ovidiu Hategan pointed to the spot when Dinamo keeper Jaime Penedo clattered into Brazilian midfielder William De Amorim moments after kickoff on Wednesday. Romania’s soccer statisticians said it was the quickest penalty ever awarded in the country’s top flight. Another Brazilian midfielder, Fernando Boldrin, made no mistake from the spot, but Dinamo overcame the early setback to complete a 3-1 victory. (Reporting by Angel Krasimirov; editing by Toby Davis)...

One day after President Donald Trump’s valet tested positive for COVID-19, Pence’s press secretary Katie Miller confirmed she also tested positive on Friday. The vice president’s spokesperson, Devin M. O’Malley, told Newsweek Sunday that Pence “is not in quarantine” and “will continue to follow the advice of the White House Medical Unit.” “Additionally, Vice President Pence has tested negative every single day and plans to be at the White House tomorrow,” he said....

It’s the last scheduled home game for Pitt in this rivalry for the foreseeable future. The Panthers pulled out all the stops under the primetime spotlight, too. Pitt rushed for 214 yards in the first half before program legends Bill Fralic, Dan Marino, Tony Dorsett, Hugh Green and Mike Ditka were honored as part of the school’s inaugural Hall of Fame class. The Nittany Lions might have been up against the elements, but they were never out of their element in a 51-6 blowout....

And he was one College Football Hall of Famer raving about his pro prospects. Barkley has 649 rushing yards and six rushing touchdowns this year, despite teams stacking the box to try to limit him. And Jack Ham, one of the best linebackers in NFL history as well as a Penn State alum, thinks Barkley is ready to excel on Sundays. MORE: Penn State vs. Michigan: A history of big names in bigger games Ham, a Pro Football Hall of Fame linebacker with eight Pro Bowl selections as well as four Super Bowl rings, thinks Barkley is one of the best players in the country and fully deserving of the Heisman buzz....

Angels second baseman Johnny Giavotella hit a two-out single to score the tying run and the go-ahead run in the ninth inning. He finished the game 3 for 5 with three RBIs and gave Los Angeles another shot at a postseason berth. MORE: MLB playoff scenarios The Rangers, on the other hand, had a chance to clinch the division before the meltdown. Closer Shawn Tolleson gave up back to back home runs to Erick Aybar and Kole Calhoun to cut Texas’ lead from four to two to start the ninth inning....

Arrieta, who owns a 0.48 ERA since the start of August, became the fifth Cubs pitcher in the last 100 years to be the first in the big leagues to 20 wins. MORE: Yogi Berra dies at 90 | Classic photos of Yogi Berra Kris Bryant drove in three of the four Cubs runs in support of Arrieta, including his 26th homer of the season to pass Hall of Famer Billy Williams for the franchise rookie record....

Pennsylvania was a must-win for President Donald Trump, as there was no way for him to reach 270 electoral votes without it. Even if he were to win every other outstanding state—Nevada, North Carolina, Georgia and Alaska—it wouldn’t be enough to secure re-election. Trump had prematurely declared victory in Pennsylvania on Wednesday even as millions of votes had yet to be counted. Bill Stepien, the president’s campaign manager, said in a press call that “We are declaring a victory in Pennsylvania....

Taipei-based United Daily News said members of the U.S. Marine Raiders had been invited to Taiwan for a four-week training session starting Monday, but the island’s Ministry of National Defense also refuted the details, saying they were “not true.” The Raiders were reportedly charged with overseeing a group of Taiwanese Marines, who were to be taught techniques including amphibious assault operations and speedboat infiltration, the newspaper said. This came after Taiwan’s Naval Command issued a rare statement Monday in response to local media reports claiming American troops were at the Tsoying Naval Base in the southwestern port city of Kaohsiung....

The homeowner, based in Fort Myers, Florida, has been sharing a series of clips to their TikTok account, @keyrealtors, documenting the saga with the HOA, thought to be Castle Group. Earlier this month, they posted a video, explaining: “My homeowners association denied my decorative garage door hinges. “When I asked if everyone with a decorative wall hanging applied for approval, the board changed the rules and removed decorative wall décor from needing approval....

The Spaniard’s current contract with Manchester City expires in 2021, leading many to believe that he will leave the Cityzens to re-join Barcelona and take the club back to the top of European football. Guardiola is, however, reportedly keener to sign a contract extension with Manchester City rather than to make a return to Catalonia. Manchester City have had a below-par start to their 2020-21 Premier League campaign and are coming off the back of a 2019-20 season where they finished 18 points behind eventual winners, Liverpool....

City are eyeing a third consecutive Premier League crown under Guardiola, however, the defending champions are third and 14 points adrift of unbeaten rivals Liverpool – who have a game in hand – after 20 matches. Amid doubts over Guardiola’s long-term future in Manchester, former Barcelona star Xavi believes the Spaniard will prioritise the Champions League ahead of a blockbuster last-16 showdown against Real Madrid. “Pep is a born winner,” Al Sadd head coach Xavi, who played under Guardiola at Camp Nou, told The Mirror....

Percocet is an opioid, which means that it is a morphine-based medication and should be taken with caution. It is known by several brand names, including Primlev, Roxicet, Endocet, and Xartemis XR. Uses Percocet is used for the treatment of moderate to severe pain. It typically is used for a short time during the early days of postsurgical recovery. Patients may have difficulty coughing or performing limited amounts of exercise like taking short walks due to pain, which increases the risk of pneumonia (an infection of the lungs) and blood clots after surgery....

Perera returned figures of 5/55 as Sri Lanka picked up seven wickets in the last eight overs of Afghanistan innings on a pitch that looked to be on the slower side. Opting to bat after winning the toss, Afghanistan were off to a cautious start with the openers Mohammad Shahzad (34) and Ihsanullah Janat (45) putting on 57 runs in just under 12 overs. Spinner Akila Dhananjaya made the first breakthrough when he had Shahzad trapped in front of the wicket....

The Bush administration’s proposed 2008 budget guts the coffers of the U.S. Agency for International Development (which is devoted to areas like health care, education and child welfare) by 31 percent and its operations by 15 percent; meanwhile, it kicks 27 percent more money into the State Department’s economic-support fund. That means America will use more dollars to make friends and to compete in the developing world with Beijing....

Perotti collected the ball on the left side edge of the penalty area but found a Plzen defender blocking his way to goal. He initially looked as if he would try to get to the byline but then wrapped his right foot around the back of his standing left leg and chipped the ball into the far corner. The Argentine forward’s celebrations were muted, immediately suggesting that the goal was a fluke....

Persona 3 Portable first released on the PlayStation Portable in Japan in November 2009 before arriving in North America in 2010, and later in Europe in 2011. This remake of the cult classic PS2 JRPG combines elements from the original version and Persona 3 FES, an expanded re-release that made numerous changes and added a story epilogue called The Answer. While this epilogue was not included in Portable, the remake introduced many elements also introduced in Persona 4 in 2008 such as controllable party members in combat....

Atlus has never shied away from porting any of its franchises to PC, despite its release history largely tethered to PlayStation consoles. There’s never been an exclusivity deal of some kind brokered for Persona, so it is possible that the incredibly popular series could be sending more titles to PC in the future. Whether it’s more ports or further entries, the future of the series may be bright on PC....

The Costume Store was one of the many new features added in Persona 4 Golden, an enhanced remake of the original Persona 4. Located in upscale Okina City, the Store allowed players to purchase cosmetic outfits both for individual characters and for the playable Investigation Team as a whole. While most outfits only changed characters’ appearances, some came with additional changes such as battle music and in-combat voice lines. Since Golden, costumes have made appearances in both main series entries such as Persona 5 Royal and spinoffs including the various Persona Dancing games....

Just like its previous incarnation, there are various editions of Persona 5 Royal. Here is a break down of what each one comes with, as well as what kind of pre-order bonuses to look forward to. RELATED: New Persona 5 Royal English Trailer Highlights the Phantom Thieves Crew Persona 5 Royal Steelbook Pre-order Bonuses Priced at $59.99, this version comes with the game, a Steelbook case, and a downloadable dynamic PS4 theme....